Opportunity Information: Apply for PAR 24 333
The NIA Predoctoral Fellowship Award to Promote Broad Participation in Translational Research for AD/ADRD (F31 Clinical Trial Not Allowed) is a National Institutes of Health funding opportunity designed to strengthen and diversify the pipeline of scientists working on Alzheimer’s disease and Alzheimer’s disease-related dementias. The program focuses on supporting promising predoctoral researchers from diverse backgrounds by funding a structured research training experience that builds practical translational research skills. In this context, “translational” is meant broadly: projects and training can span population-based studies, behavioral and social research, and biomedical work aimed at identifying or advancing new approaches for diagnosis, treatment, prevention, early detection, and improved disease management and care. The long-range aim is not only to support an individual trainee’s dissertation research, but also to help develop a workforce that can contribute to and eventually lead interdisciplinary, team-science efforts in AD/ADRD.
This opportunity is issued by NIH under Funding Opportunity Number PAR-24-333, within the health funding category (CFDA 93.866). The funding instrument is a grant, specifically an NIH fellowship mechanism (F31) that supports predoctoral training rather than a traditional research project grant. A key restriction is built into the title and scope: clinical trials are not allowed under this NOFO. In practice, that means applicants should propose training and research activities that do not include conducting an NIH-defined clinical trial, even if the broader AD/ADRD field often intersects with clinical intervention research. The fellowship emphasis is on training development and translational skill-building aligned with AD/ADRD research priorities.
Eligibility for applicant organizations is broad and includes many types of U.S.-based entities that commonly participate in NIH funding. Eligible applicants listed include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (in both cases, other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other eligible entities. The NOFO also highlights categories of institutions and organizations that are often central to broadening participation in biomedical research, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also notes eligibility for faith-based or community-based organizations, eligible agencies of the federal government, regional organizations, Indian/Native American Tribal Governments (other than federally recognized), and U.S. territories or possessions.
At the same time, there are important geographic and organizational constraints related to foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply as applicant organizations, and non-domestic components of U.S. organizations are not eligible to apply. However, “foreign components” as defined in the NIH Grants Policy Statement are allowed, which generally means that limited, justified parts of the training or research may occur abroad or involve foreign collaborations under NIH’s rules, even though the applicant organization itself must be eligible and domestic.
The opportunity was created on 2025-01-17, and the original closing date listed is 2027-12-08, indicating an extended window during which applications may be accepted according to the NOFO’s submission schedule. The summary information provided does not specify an award ceiling or the expected number of awards, which is common in NIH fellowship announcements where final numbers depend on application volume, merit review outcomes, and available appropriations. Overall, the program is best understood as a targeted predoctoral training investment by NIA: it is meant to expand who participates in AD/ADRD translational research and to prepare trainees to work effectively in cross-disciplinary teams addressing real-world challenges in dementia prevention, detection, treatment development, and care.Apply for PAR 24 333
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIA Predoctoral Fellowship Award to Promote Broad Participation in Translational Research for AD/ADRD (F31 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
- This funding opportunity was created on 2025-01-17.
- Applicants must submit their applications by 2027-12-08.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NIA Predoctoral Fellowship Award to Promote Broad Participation in Translational Research for AD/ADRD (F31; Clinical Trial Not Allowed)
What is this funding opportunity?
This opportunity is the NIA Predoctoral Fellowship Award to Promote Broad Participation in Translational Research for Alzheimer’s disease (AD) and Alzheimer’s disease-related dementias (AD/ADRD). It is an NIH fellowship (F31) that supports a structured predoctoral research training experience aimed at building practical translational research skills in the AD/ADRD space.
What is the goal of the program?
The program is designed to strengthen and diversify the pipeline of scientists working on AD/ADRD. It supports promising predoctoral researchers from diverse backgrounds and helps develop a workforce prepared to contribute to (and eventually lead) interdisciplinary, team-science efforts focused on real-world dementia challenges.
Is this a research grant or a training fellowship?
It is a training fellowship mechanism (NIH F31), not a traditional research project grant. The emphasis is on training development and translational skill-building aligned with AD/ADRD research priorities, while also supporting the trainee’s dissertation-related research within that training plan.
Who is the issuing agency?
The opportunity is issued by the National Institutes of Health (NIH), through the National Institute on Aging (NIA).
What is the Funding Opportunity Number (NOFO)?
The Funding Opportunity Number is PAR-24-333.
What is the funding instrument and mechanism?
The funding instrument is a grant, using the NIH fellowship mechanism F31 (predoctoral fellowship).
What health funding category and CFDA number are associated with this opportunity?
The opportunity is in the health funding category and is associated with CFDA 93.866.
What does “translational research” mean in this program?
“Translational” is defined broadly for this fellowship. Projects and training may span population-based studies, behavioral and social research, and biomedical work aimed at identifying or advancing approaches to diagnosis, treatment, prevention, early detection, and improved disease management and care for AD/ADRD.
What kinds of AD/ADRD topics are a fit for this fellowship?
Based on the program description, a fit can include work connected to diagnosis, treatment development, prevention, early detection, and improved management and care of AD/ADRD, as long as the proposed training and research activities align with a structured predoctoral training experience and remain within the “clinical trial not allowed” restriction.
Are clinical trials allowed?
No. Clinical trials are not allowed under this NOFO. Applicants should propose training and research activities that do not include conducting an NIH-defined clinical trial.
If my field overlaps with clinical intervention work, can I still apply?
Yes, the broader AD/ADRD field can overlap with clinical intervention research, but this fellowship specifically requires that the proposed activities do not include conducting an NIH-defined clinical trial. The application should stay within non-clinical-trial training and research activities.
Who can apply as an applicant organization?
Eligibility for applicant organizations is broad and includes many U.S.-based entity types commonly participating in NIH funding, including government entities, higher education institutions, nonprofits, and for-profit organizations (including small businesses), as described in the NOFO summary.
What types of U.S. government entities are eligible to apply?
Eligible government entities listed include state governments; county governments; city or township governments; and special district governments.
Are schools and universities eligible?
Yes. Eligible applicants include independent school districts and institutions of higher education (both public/state-controlled and private).
Are nonprofits eligible?
Yes. The eligible applicants list includes nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (in both cases, other than institutions of higher education).
Are for-profit organizations eligible?
Yes. The eligible applicants list includes for-profit organizations (other than small businesses) and small businesses.
Are Tribal entities eligible?
Yes. The eligible applicants list includes federally recognized Native American tribal governments and Native American tribal organizations that are not federally recognized tribal governments. The summary also references Indian/Native American Tribal Governments (other than federally recognized).
Are U.S. territories or possessions eligible?
Yes. The summary notes eligibility for U.S. territories or possessions.
Are faith-based or community-based organizations eligible?
Yes. The summary explicitly notes eligibility for faith-based or community-based organizations.
Are federal agencies eligible to apply?
Yes. The summary notes eligibility for eligible agencies of the federal government.
Are regional organizations eligible?
Yes. The summary notes eligibility for regional organizations.
Does the NOFO encourage or highlight certain institution types connected to broadening participation?
Yes. The NOFO highlights categories of institutions and organizations often central to broadening participation in biomedical research, including HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
Can a foreign (non-U.S.) organization apply as the applicant organization?
No. Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply as applicant organizations.
Can a non-domestic component of a U.S. organization apply?
No. Non-domestic components of U.S. organizations are not eligible to apply as applicant organizations.
Are any international activities allowed at all?
Yes, “foreign components” (as defined in the NIH Grants Policy Statement) are allowed. This generally means limited, justified parts of the training or research may occur abroad or involve foreign collaborations under NIH rules, even though the applicant organization itself must be eligible and domestic.
When was this opportunity created?
The opportunity was created on 2025-01-17.
What is the closing date?
The original closing date listed is 2027-12-08. The summary indicates an extended window during which applications may be accepted according to the NOFO’s submission schedule.
Is there an award ceiling listed?
The summary information provided does not specify an award ceiling.
How many awards will be made?
The summary information provided does not specify an expected number of awards. For NIH fellowship announcements, final numbers can depend on application volume, merit review outcomes, and available appropriations.
What is the long-range aim beyond funding one trainee?
Beyond supporting an individual trainee’s dissertation research within a structured training plan, the long-range aim is to help develop a diverse AD/ADRD translational research workforce capable of contributing to and leading interdisciplinary, team-science efforts over time.
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