Provision of Comprehensive HIV Prevention, Care, Treatment, and Support Programs in the United Republic of Tanzania under the President's Emergency Plan for AIDS Relief (PEPFAR) | CDC RFA GH18 1811

Opportunity Information: Apply for CDC RFA GH18 1811

The Centers for Disease Control and Prevention (CDC), through PEPFAR, issued this Notice of Funding Opportunity (NOFO) to support comprehensive HIV prevention, care, treatment, and support services in Tanzania in alignment with the Government of Tanzania (GOT) HIV Strategic Plan. The opportunity is designed to strengthen the full clinical cascade, meaning the end-to-end pathway from identifying people living with HIV, linking them to care, starting and maintaining effective treatment, and confirming treatment success through viral load monitoring. A major emphasis is on ensuring that services are high quality, data-driven, and sustainable through strong quality assurance systems, reliable laboratory services, and effective data management practices.

At the core of the program is the expectation that recipients will implement innovative and evidence-based interventions that are realistic, measurable, culturally appropriate, and achievable in the Tanzanian context. The NOFO highlights targeted index patient testing as a key strategy for finding undiagnosed HIV infections, paired with rapid linkage to care and treatment clinics (CTCs). Once individuals are diagnosed, the program prioritizes same-day initiation of antiretroviral therapy (ART) where clinically appropriate, followed by strong retention and adherence support so patients remain engaged in care over time. Viral load (VL) monitoring is a central metric for success, with the goal of achieving and sustaining viral suppression at the population level, which improves individual health outcomes and reduces onward transmission.

The opportunity also makes clear that treatment programs are not limited to facility-based care. Recipients are expected to support community-based HIV services that help maintain continuity of care, particularly in districts categorized as "sustained" councils where maintaining gains and preventing backsliding are critical. This includes designing services that reduce barriers to care, improve follow-up, and support long-term engagement for people on ART. The approach is meant to be comprehensive and integrated, including attention to co-morbidities and service delivery challenges that affect outcomes across the cascade.

Coordination with government health structures is a required feature of the award. Implementers must work closely with regional and district health management teams to plan and execute care and treatment activities at the facility level while meeting both PEPFAR goals and the priorities set out in Tanzania's National Multi-Sectoral Strategic Framework IV (NMSF IV). This collaboration is intended to strengthen local ownership, improve alignment with national systems, and ensure that improvements in service delivery are institutionalized rather than dependent on parallel structures.

Population coverage is broad but clearly prioritized. The NOFO specifies focus on adults and children, HIV-infected pregnant women and lactating mothers (reflecting prevention of mother-to-child transmission and maternal health priorities), TB-HIV co-infected patients (given the clinical complexity and public health importance of co-infection), and key populations (KP) along with other defined priority groups. This signals an expectation that implementers will tailor service models to different clinical and social needs, including differentiated approaches for pediatrics, maternal populations, and groups facing heightened vulnerability or barriers to access.

Geographically, the program targets implementation across five regions: Kigoma, Pwani, Dar es Salaam, Kagera, and Zanzibar. Activities are planned for a mix of "scale-up" and "sustained" districts, specifically 16 scale-up districts and 20 sustained districts, reflecting a strategy that combines expansion of high-impact services in higher-need areas with maintenance of achievements where progress has already been made. The NOFO notes that district selections may change over time as the epidemic burden and evidence evolve, implying that implementers must be adaptable and capable of re-targeting resources based on updated epidemiologic data and program performance.

From an administrative standpoint, this is a discretionary funding opportunity offered as a cooperative agreement, which typically means substantial programmatic involvement by the funding agency compared with a standard grant. The opportunity number is CDC RFA GH18 1811 under CFDA 93.067, and eligibility is listed as unrestricted, allowing a wide range of applicant organizations to compete. The award ceiling is $60,000,000, with an expectation of two awards, indicating large-scale implementation intended to cover significant portions of the care and treatment portfolio in the target areas. The original closing date listed is January 6, 2020, and the opportunity was created on September 26, 2017, placing it in the context of PEPFAR programming cycles and national planning periods during that timeframe.

• The Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Provision of Comprehensive HIV Prevention, Care, Treatment, and Support Programs in the United Republic of Tanzania under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
• This funding opportunity was created on 2017-09-26.
• Applicants must submit their applications by 2020-01-06. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $60,000,000.00 in funding.
• The number of recipients for this funding is limited to 2 candidate(s).
• Eligible applicants include: Unrestricted.

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