Opportunity Information: Apply for CDC RFA GH18 1811
The Centers for Disease Control and Prevention (CDC), through PEPFAR, issued this Notice of Funding Opportunity (NOFO) to support comprehensive HIV prevention, care, treatment, and support services in Tanzania in alignment with the Government of Tanzania (GOT) HIV Strategic Plan. The opportunity is designed to strengthen the full clinical cascade, meaning the end-to-end pathway from identifying people living with HIV, linking them to care, starting and maintaining effective treatment, and confirming treatment success through viral load monitoring. A major emphasis is on ensuring that services are high quality, data-driven, and sustainable through strong quality assurance systems, reliable laboratory services, and effective data management practices.
At the core of the program is the expectation that recipients will implement innovative and evidence-based interventions that are realistic, measurable, culturally appropriate, and achievable in the Tanzanian context. The NOFO highlights targeted index patient testing as a key strategy for finding undiagnosed HIV infections, paired with rapid linkage to care and treatment clinics (CTCs). Once individuals are diagnosed, the program prioritizes same-day initiation of antiretroviral therapy (ART) where clinically appropriate, followed by strong retention and adherence support so patients remain engaged in care over time. Viral load (VL) monitoring is a central metric for success, with the goal of achieving and sustaining viral suppression at the population level, which improves individual health outcomes and reduces onward transmission.
The opportunity also makes clear that treatment programs are not limited to facility-based care. Recipients are expected to support community-based HIV services that help maintain continuity of care, particularly in districts categorized as "sustained" councils where maintaining gains and preventing backsliding are critical. This includes designing services that reduce barriers to care, improve follow-up, and support long-term engagement for people on ART. The approach is meant to be comprehensive and integrated, including attention to co-morbidities and service delivery challenges that affect outcomes across the cascade.
Coordination with government health structures is a required feature of the award. Implementers must work closely with regional and district health management teams to plan and execute care and treatment activities at the facility level while meeting both PEPFAR goals and the priorities set out in Tanzania's National Multi-Sectoral Strategic Framework IV (NMSF IV). This collaboration is intended to strengthen local ownership, improve alignment with national systems, and ensure that improvements in service delivery are institutionalized rather than dependent on parallel structures.
Population coverage is broad but clearly prioritized. The NOFO specifies focus on adults and children, HIV-infected pregnant women and lactating mothers (reflecting prevention of mother-to-child transmission and maternal health priorities), TB-HIV co-infected patients (given the clinical complexity and public health importance of co-infection), and key populations (KP) along with other defined priority groups. This signals an expectation that implementers will tailor service models to different clinical and social needs, including differentiated approaches for pediatrics, maternal populations, and groups facing heightened vulnerability or barriers to access.
Geographically, the program targets implementation across five regions: Kigoma, Pwani, Dar es Salaam, Kagera, and Zanzibar. Activities are planned for a mix of "scale-up" and "sustained" districts, specifically 16 scale-up districts and 20 sustained districts, reflecting a strategy that combines expansion of high-impact services in higher-need areas with maintenance of achievements where progress has already been made. The NOFO notes that district selections may change over time as the epidemic burden and evidence evolve, implying that implementers must be adaptable and capable of re-targeting resources based on updated epidemiologic data and program performance.
From an administrative standpoint, this is a discretionary funding opportunity offered as a cooperative agreement, which typically means substantial programmatic involvement by the funding agency compared with a standard grant. The opportunity number is CDC RFA GH18 1811 under CFDA 93.067, and eligibility is listed as unrestricted, allowing a wide range of applicant organizations to compete. The award ceiling is $60,000,000, with an expectation of two awards, indicating large-scale implementation intended to cover significant portions of the care and treatment portfolio in the target areas. The original closing date listed is January 6, 2020, and the opportunity was created on September 26, 2017, placing it in the context of PEPFAR programming cycles and national planning periods during that timeframe.Apply for CDC RFA GH18 1811
- The Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Provision of Comprehensive HIV Prevention, Care, Treatment, and Support Programs in the United Republic of Tanzania under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on 2017-09-26.
- Applicants must submit their applications by 2020-01-06. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $60,000,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted.
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Frequently Asked Questions (FAQs)
1) What is this funding opportunity about?
This Notice of Funding Opportunity (NOFO) from the Centers for Disease Control and Prevention (CDC), through PEPFAR, supports comprehensive HIV prevention, care, treatment, and support services in Tanzania. It is designed to align with the Government of Tanzania (GOT) HIV Strategic Plan and related national priorities.
2) What is the main program goal?
The central goal is to strengthen the full clinical cascade (the end-to-end pathway from identifying people living with HIV to confirming treatment success through viral load monitoring). The NOFO emphasizes high-quality, data-driven, and sustainable services supported by strong quality assurance systems, reliable laboratory services, and effective data management.
3) What does "full clinical cascade" mean in this NOFO?
In this opportunity, the full clinical cascade includes identifying people living with HIV (including finding undiagnosed infections), linking diagnosed individuals to care, initiating effective treatment (including same-day ART when clinically appropriate), supporting retention and adherence over time, and confirming treatment success through viral load monitoring and suppression.
4) What strategies are emphasized for finding undiagnosed HIV infections?
The NOFO highlights targeted index patient testing as a key strategy to identify previously undiagnosed HIV infections, paired with rapid linkage to care and treatment clinics (CTCs).
5) What is expected after someone is diagnosed with HIV?
Recipients are expected to prioritize rapid linkage to care and treatment clinics (CTCs). The NOFO further prioritizes same-day initiation of antiretroviral therapy (ART) where clinically appropriate, followed by strong retention and adherence support.
6) Is same-day ART required for all clients?
The NOFO emphasizes same-day ART initiation where clinically appropriate. This indicates an expectation to implement same-day ART as a priority approach, while still considering clinical appropriateness.
7) Why is viral load monitoring emphasized?
Viral load (VL) monitoring is described as a central metric for success. The goal is to achieve and sustain viral suppression at the population level, improving individual health outcomes and reducing onward HIV transmission.
8) Are services limited to facility-based care?
No. The NOFO states that treatment programs are not limited to facility-based care. Recipients are expected to support community-based HIV services to maintain continuity of care and reduce barriers to long-term engagement, particularly in districts categorized as "sustained" councils.
9) What is the difference between "scale-up" and "sustained" districts in this NOFO?
The NOFO plans activities across both "scale-up" and "sustained" districts. Scale-up districts reflect expansion of high-impact services in higher-need areas, while sustained districts focus on maintaining gains and preventing backsliding where progress has already been achieved.
10) How many districts are included?
The NOFO describes implementation across 16 scale-up districts and 20 sustained districts.
11) Can the targeted districts change over time?
Yes. The NOFO notes that district selections may change over time as epidemic burden and evidence evolve. This implies implementers should be adaptable and able to re-target resources based on updated epidemiologic data and program performance.
12) What regions in Tanzania are targeted?
The NOFO targets implementation across five regions: Kigoma, Pwani, Dar es Salaam, Kagera, and Zanzibar.
13) Which populations are prioritized for services?
The NOFO specifies a focus on adults and children, HIV-infected pregnant women and lactating mothers, TB-HIV co-infected patients, key populations (KP), and other defined priority groups.
14) Does the NOFO require tailoring services for different groups?
Yes. The NOFO signals an expectation that implementers tailor service models to different clinical and social needs, including differentiated approaches for pediatrics, maternal populations, and groups that face heightened vulnerability or barriers to access.
15) How should implementers work with the Government of Tanzania?
Coordination with government health structures is a required feature of the award. Implementers must work closely with regional and district health management teams to plan and execute facility-level care and treatment activities while meeting PEPFAR goals and the priorities in Tanzania's National Multi-Sectoral Strategic Framework IV (NMSF IV).
16) What is the intent behind government coordination requirements?
The NOFO frames this collaboration as a way to strengthen local ownership, align activities with national systems, and ensure improvements are institutionalized rather than dependent on parallel structures.
17) What type of funding mechanism is this?
This is a discretionary funding opportunity offered as a cooperative agreement. The NOFO notes that cooperative agreements typically involve substantial programmatic involvement by the funding agency compared with a standard grant.
18) What is the opportunity number and CFDA listing?
The opportunity number is CDC RFA GH18 1811, under CFDA 93.067.
19) Who is eligible to apply?
Eligibility is listed as unrestricted, meaning a wide range of applicant organizations may compete, based on the information provided in the NOFO summary.
20) What is the maximum award amount (ceiling)?
The award ceiling is $60,000,000.
21) How many awards are expected?
The NOFO indicates an expectation of two awards.
22) What does the NOFO say about innovation and evidence-based interventions?
Recipients are expected to implement innovative and evidence-based interventions that are realistic, measurable, culturally appropriate, and achievable in the Tanzanian context.
23) What operational capabilities are emphasized for sustainability and performance?
The NOFO emphasizes strong quality assurance systems, reliable laboratory services, and effective data management practices as core elements supporting high-quality, data-driven, and sustainable HIV services.
24) Are co-morbidities addressed in this program?
Yes. The NOFO describes the approach as comprehensive and integrated, including attention to co-morbidities and service delivery challenges that affect outcomes across the cascade. TB-HIV co-infection is specifically called out as a priority area.
25) What is the original closing date and when was the opportunity created?
The original closing date listed is January 6, 2020. The opportunity was created on September 26, 2017.
26) How does this NOFO relate to national and PEPFAR planning?
The NOFO is framed as aligned with the GOT HIV Strategic Plan and Tanzania's NMSF IV, and it is placed in the context of PEPFAR programming cycles and national planning periods during the timeframe referenced.
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