Opportunity Information: Apply for RFA NS 17 024
The Clinical Research Sites for the Network of Excellence in Neuroscience Clinical Trials (NeuroNEXT sites) (U24) funding opportunity (RFA-NS-17-024) is a cooperative agreement issued by the National Institute of Neurological Disorders and Stroke (NINDS) within the NIH. Its main goal is to support a set of clinical research sites that can participate in NeuroNEXT, a standing national network designed to efficiently develop and run multiple neuroscience clinical studies and exploratory trials. Rather than funding a single disease-specific project, this mechanism helps maintain site readiness and performance so the network can rapidly launch well-designed studies across a range of neurological disorders as promising therapies and research questions emerge.
A key emphasis of the program is conducting scientifically rigorous, exploratory clinical trials that can move the field toward more definitive testing. The FOA highlights examples such as Phase 2 clinical trials, as well as clinical research efforts focused on validating biomarkers and clinical outcome measures that are needed before larger confirmatory trials can be successful. In practice, this means the network is positioned to test interventions and approaches coming from academic labs, foundations, or industry partners, including studies that may be biomarker-informed (for example, selecting participants based on biological signals or using biomarkers to measure treatment response). The larger purpose is to improve the speed, consistency, and quality of multicenter neuroscience trials by relying on experienced, well-coordinated sites that share processes and expectations.
The award is structured as a cooperative agreement (U24), which generally signals substantial NIH involvement compared with a standard grant. Under this model, funded sites are expected to work closely with NINDS and the NeuroNEXT network leadership on planning and executing trials, following common protocols and operational standards. The intent is to create a coordinated infrastructure where each clinical site can contribute to participant recruitment, study conduct, and high-quality data collection across multiple studies over time, rather than building a new trial infrastructure from scratch for every new protocol.
Eligibility is broad and includes many types of organizations that can function as clinical research sites. Eligible applicants include state, county, and local governments; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (including small businesses and other for-profits); tribal governments and tribal organizations; public housing authorities/Indian housing authorities; and other entities as allowed by the FOA’s additional eligibility language. This range reflects the program’s focus on enrolling capable clinical sites wherever they exist, provided they can meet the operational demands of network-based, multicenter neuroscience studies.
From an administrative and funding perspective, the opportunity falls under the Health activity category and is associated with CFDA 93.853. The FOA information indicates an anticipated number of awards of about 25, with an award ceiling of $200,000. The posting lists a creation date of June 30, 2017, and an original closing date of September 1, 2017. Overall, the opportunity is best understood as a way for NINDS to maintain and expand a ready-to-activate network of high-performing clinical sites capable of running multiple, coordinated neuroscience clinical trials and biomarker/outcome validation studies, accelerating the translation of promising therapeutic ideas into well-executed human research.Apply for RFA NS 17 024
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Clinical Research Sites for the Network of Excellence in Neuroscience Clinical Trials (NeuroNEXT sites) (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853.
- This funding opportunity was created on Jun 30, 2017.
- Applicants must submit their applications by Sep 01, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- The number of recipients for this funding is limited to 25 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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